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Tokyo's benchmark Nikkei index dropped more than four percent on Wednesday amid a broader market rout over the coronavirus outbreak, with fears growing of a possible lockdown in the capital.

The Nikkei 225 index lost 4.50 percent, or 851.60 points, to close at 18,065.41 while the broader Topix index dropped 3.70 percent, or 51.96 points, to 1,351.08.