File photo: VCG

Tokyo stocks opened lower on Thursday, shrugging off rallies on Wall Street, as investors digested US economic indicators, vaccine news, and earnings reports.

The benchmark Nikkei 225 index was down 0.25 percent or 56.11 points at 22,458.74 in early trade, while the broader Topix index slipped 0.33 percent or 5.08 points to 1,549.63.