(File photo: social media)

TOKYO, June 5 (Xinhua) -- Tokyo stocks opened lower Friday after U.S. shares lost ground overnight, with investors opting to lock in profits following the market's recent gains while eyeing U.S. jobs data due out later in the day likely to show the unemployment rate has hit a fresh record high.

As of 9:15 a.m., the 225-issue Nikkei Stock Average dropped 51.85 points, or 0.23 percent, from Thursday to 22,643.89.

The broader Topix index of all First Section issues on the Tokyo Stock Exchange, meanwhile, lost 1.77 points, or 0.11 percent, at 1,602.05.

Precision instrument, service and pharmaceutical-linked issues led those that declined the most in the opening minutes after the morning bell.