CHINA Chinese mRNA-based COVID vaccines effective in preclinical trials

CHINA

Chinese mRNA-based COVID vaccines effective in preclinical trials

Xinhua

16:57, June 11, 2022

BEIJING, June 11 (Xinhua) -- Two mRNA-based COVID-19 vaccine candidates produced by Chinese manufacturer CanSino Biologics have proven effective in preclinical trials, suggesting the potential for human tests, according to a new study published in the journal Emerging Microbes & Infections.

File photo: CFP

Results showed that the two vaccines, the mRNA-Beta and mRNA-Omicron, can induce high-titer neutralizing antibody levels against original and multiple SARS-CoV-2 variants, such as Beta, Delta and Omicron.

Two doses of mRNA-Beta could induce broad protection especially for Beta and original variants. Meanwhile, mRNA-Omicron was suggested as a booster injection in mice vaccinated with primary mRNA-Beta or Ad5-nCoV, the company's recombinant COVID-19 vaccine, to offer further protection against Omicron variant, according to the study.

The Chinese mRNA vaccines got clinical trial approval in April and they have entered phase-1 human trials, according to a company statement released this week.

Compared with traditional vaccine technologies, the mRNA technology has the advantage of a shorter development and production cycle.

The Chinese vaccine maker said an industrialization base of the COVID-19 mRNA vaccine was under construction in Shanghai. It will enable the annual production capacity to reach 100 million doses by the end of 2022.

Terms of Service & Privacy Policy

We have updated our privacy policy to comply with the latest laws and regulations. The updated policy explains the mechanism of how we collect and treat your personal data. You can learn more about the rights you have by reading our terms of service. Please read them carefully. By clicking AGREE, you indicate that you have read and agreed to our privacy policies

Agree and continue