The latest: COVID-19 outbreak worldwide (Updated April 22)
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Globally, as of 2:00 am CEST on Tuesday, there have been 2,402,250 confirmed cases of COVID-19, including 163,097 deaths, reported to WHO.

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A member of the Venezuelan civil protection agency explains commuters symptoms and preventive measures for the new coronavirus in Caracas, Venezuela, Sunday, March 15, 2020. (Photo: AP)

Current status (data as of 6 pm BJT, April 22):

10 countries_regions with the most confirmed COVID-19 cases outside China .jpg

Sources: Xinhua, Johns Hopkins University, national public health agencies.

The outbreak has now claimed the lives of at least 45,447 people in the US, the most of any country. The US also leads the world in the number of confirmed infections with 827,358, according to a tally by Johns Hopkins University as of 6 pm BJT on Wednesday.

Spain has reported 21,717 deaths from COVID-19, with the tally of infections reaching 208,389.

The coronavirus pandemic has claimed 24,648 lives in locked-down Italy, bringing the total number of infections to 183,957, according to the latest data released by the country's Civil Protection Department on Tuesday.

The total number of infections in France has increased to 159,300, Johns Hopkins reported.

It is followed by Germany with 5,086 deaths from 148,453 infections.

The UK has a total of 130,184 people who have tested positive for COVID-19, with the death toll at 17,378.

The number of COVID-19 cases has increased to 95,591 in Turkey while the death toll surged to 2,259, Turkish Health Minister Fahrettin Koca tweeted.

Iran recorded 94 new COVID-19 deaths in the past 24 hours, bringing the death toll to 5,391 in the country. The total number of infections has reached 85,996, according to its health ministry.

Russia has registered a total of  57,999 infections and 513 fatalities, according to the JHU virus tracker.

Confirmed cases of COVID-19 in Brazil increased to 43,368 with 2,761 deaths, Johns Hopkins reported.